Abstract
The time, temperature, and sequence dependences of helix formation kinetics of fully atomistic peptide models in explicit solvent are described quantitatively by a diffusive search within the coil state with barrierless transitions into the helical state. Conformational diffusion leads to nonexponential kinetics and jump-width dependences in temperature jump experiments.
- Received 21 April 2000
DOI:https://doi.org/10.1103/PhysRevLett.85.2637
©2000 American Physical Society