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Synthesis of Programmable Reaction-Diffusion Fronts Using DNA Catalyzers

Anton S. Zadorin, Yannick Rondelez, Jean-Christophe Galas, and André Estevez-Torres
Phys. Rev. Lett. 114, 068301 – Published 9 February 2015
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Abstract

We introduce a DNA-based reaction-diffusion (RD) system in which reaction and diffusion terms can be precisely and independently controlled. The effective diffusion coefficient of an individual reaction component, as we demonstrate on a traveling wave, can be reduced up to 2.7-fold using a self-assembled hydrodynamic drag. The intrinsic programmability of this RD system allows us to engineer, for the first time, orthogonal autocatalysts that counterpropagate with minimal interaction. Our results are in excellent quantitative agreement with predictions of the Fisher-Kolmogorov-Petrovskii-Piscunov model. These advances open the way for the rational engineering of pattern formation in pure chemical RD systems.

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  • Received 6 October 2014

DOI:https://doi.org/10.1103/PhysRevLett.114.068301

© 2015 American Physical Society

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Making Waves with DNA

Published 9 February 2015

Strands of DNA can be used to generate waves of chemical reactions with programmable shape and velocity.

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Authors & Affiliations

Anton S. Zadorin1, Yannick Rondelez2, Jean-Christophe Galas1, and André Estevez-Torres1,*

  • 1Laboratoire de photonique et de nanostructures, CNRS, route de Nozay, 91460 Marcoussis, France
  • 2LIMMS/CNRS-IIS, University of Tokyo, Komaba, 4-6-2 Meguro-ku, Tokyo, Japan

  • *aestevez@lpn.cnrs.fr

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Issue

Vol. 114, Iss. 6 — 13 February 2015

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