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Fiber Diffraction without Fibers

H.-C. Poon, P. Schwander, M. Uddin, and D. K. Saldin
Phys. Rev. Lett. 110, 265505 – Published 27 June 2013
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Abstract

Postprocessing of diffraction patterns of completely randomly oriented helical particles, as measured, for example, in so-called “diffract-and-destroy” experiments with an x-ray free electron laser can yield “fiber diffraction” patterns expected of fibrous bundles of the particles. This will allow “single-axis alignment” to be performed computationally, thus obviating the need to do this by experimental means such as forming fibers and laser or flow alignment. The structure of such particles may then be found by either iterative phasing methods or standard methods of fiber diffraction.

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  • Received 12 September 2012

DOI:https://doi.org/10.1103/PhysRevLett.110.265505

© 2013 American Physical Society

Synopsis

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Published 27 June 2013

A new computational method would make it simpler to determine, via x-ray diffraction, the structure of molecules without aligning them.

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Authors & Affiliations

H.-C. Poon, P. Schwander, M. Uddin, and D. K. Saldin

  • Department of Physics, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, USA

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Issue

Vol. 110, Iss. 26 — 28 June 2013

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