Abstract
Transient interactions among ultrasound, microbubbles, and microvessels were studied using high-speed photomicrography. We observed liquid jets, vessel distention (motion outward against the surrounding tissue), and vessel invagination (motion inward toward the lumen). Contrary to current paradigms, liquid jets were directed away from the nearest vessel wall and invagination exceeded distention. These observations provide insight into the mechanics of bubble-vessel interactions, which appear to depend qualitatively upon the mechanical properties of biological tissues.
- Received 14 May 2010
DOI:https://doi.org/10.1103/PhysRevLett.106.034301
© 2011 American Physical Society
Synopsis
Bubble trouble
Published 31 January 2011
Measurements of microbubbles in blood vessels under ultrasonic exposure show complex behavior that might relate to potential tissue damage.
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