Emergence of metachronal waves in active microtubule arrays

Stephen E. Martin, Matthew E. Brunner, and Joshua M. Deutsch
Phys. Rev. Fluids 4, 103101 – Published 28 October 2019
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Abstract

The physical mechanism behind the spontaneous formation of metachronal waves in microtubule arrays in a low-Reynolds-number fluid has been of interest for the past several years, yet is still not well understood. We present a model implementing the hydrodynamic coupling hypothesis from first principles and use this model to simulate kinesin-driven microtubule arrays and observe their emergent behavior. The results of simulations are compared with known experimental observations by Sanchez et al. [Science 333, 456 (2011)]. By varying parameters, we determine regimes in which the metachronal wave phenomenon emerges and categorize other types of possible microtubule motion outside these regimes.

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  • Received 21 June 2018

DOI:https://doi.org/10.1103/PhysRevFluids.4.103101

©2019 American Physical Society

Physics Subject Headings (PhySH)

Physics of Living SystemsPolymers & Soft MatterFluid DynamicsNonlinear Dynamics

Authors & Affiliations

Stephen E. Martin1, Matthew E. Brunner2, and Joshua M. Deutsch1,*

  • 1Department of Physics, University of California, Santa Cruz, California 95064, USA
  • 2Voltaiq Inc. 2150 Shattuck Ave, #704 Berkeley, California 94704, USA

  • *josh@ucsc.edu

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Vol. 4, Iss. 10 — October 2019

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