Understanding the Electroporation of Cells and Artificial Bilayer Membranes

Hervé Isambert
Phys. Rev. Lett. 80, 3404 – Published 13 April 1998
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Abstract

A new physical mechanism is proposed to explain the electroporation of cells based on the electric-field-induced stretching of their curved membrane. The opening of pores simultaneously relaxes the surface tension leaving long-lived pores in the membrane. Semiquantitative results are proposed in good agreement with experimental observations on cells and artificial bilayer membranes.

  • Received 17 October 1997

DOI:https://doi.org/10.1103/PhysRevLett.80.3404

©1998 American Physical Society

Authors & Affiliations

Hervé Isambert*

  • Department of Physics, Cornell University, Ithaca, New York 14853-2501

  • *Present address: Center for Studies in Physics and Biology, The Rockefeller University, Box 25, 1230 York Avenue, New York, N.Y. 10021.

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Vol. 80, Iss. 15 — 13 April 1998

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