Cooperative Molecular Motors

Frank Jülicher and Jacques Prost
Phys. Rev. Lett. 75, 2618 – Published 25 September 1995
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Abstract

We present a simple stochastical model for motor molecules that cooperate in large groups. This model could apply for actin-myosin motors in muscles and for motility assays with a high concentration of motor molecules. We calculate the dependence of the velocity on the applied force as a function of ATP concentration and show the existence of a dynamical phase transition allowing for spontaneous directed motion even if the system is spatially symmetric. In the symmetric case, the problem is isomorphous to a paramagnet-ferromagnet transition, in the asymmetric case to a liquid-vapor transition.

  • Received 25 April 1995

DOI:https://doi.org/10.1103/PhysRevLett.75.2618

©1995 American Physical Society

Authors & Affiliations

Frank Jülicher1,2 and Jacques Prost1,3,4

  • 1Institute for Theoretical Physics, University of California, Santa Barbara, California 93106
  • 2Department of Physics, Simon Fraser University, Burnaby, British Columbia, Canada V5A 1S6
  • 3Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris, 10 rue Vauquelin, 75231 Paris Cedex 05, France
  • 4Institut Curie, 11 rue Pierre et Marie Curie, 75231 Paris Cedex 05, France

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Issue

Vol. 75, Iss. 13 — 25 September 1995

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