• Open Access

Length Regulation Drives Self-Organization in Filament-Motor Mixtures

Moritz Striebel, Fridtjof Brauns, and Erwin Frey
Phys. Rev. Lett. 129, 238102 – Published 30 November 2022

Abstract

Cytoskeletal networks form complex intracellular structures. Here we investigate a minimal model for filament-motor mixtures in which motors act as depolymerases and thereby regulate filament length. Combining agent-based simulations and hydrodynamic equations, we show that resource-limited length regulation drives the formation of filament clusters despite the absence of mechanical interactions between filaments. Even though the orientation of individual remains fixed, collective filament orientation emerges in the clusters, aligned orthogonal to their interfaces.

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  • Received 24 August 2021
  • Accepted 10 October 2022

DOI:https://doi.org/10.1103/PhysRevLett.129.238102

Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI.

Published by the American Physical Society

Physics Subject Headings (PhySH)

Nonlinear DynamicsPhysics of Living Systems

Authors & Affiliations

Moritz Striebel1,*, Fridtjof Brauns1,*, and Erwin Frey1,2,†

  • 1Arnold Sommerfeld Center for Theoretical Physics and Center for NanoScience, Department of Physics, Ludwig-Maximilians-Universität München, Theresienstrasse 37, D-80333 Munich, Germany
  • 2Max Planck School Matter to Life, Hofgartenstraße 8, D-80539 Munich, Germany

  • *M. S. and F. B. contributed equally to this work.
  • frey@lmu.de

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Vol. 129, Iss. 23 — 2 December 2022

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