Networks of Motifs from Sequences of Symbols

Roberta Sinatra, Daniele Condorelli, and Vito Latora
Phys. Rev. Lett. 105, 178702 – Published 19 October 2010
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Abstract

We introduce a method to convert an ensemble of sequences of symbols into a weighted directed network whose nodes are motifs, while the directed links and their weights are defined from statistically significant co-occurences of two motifs in the same sequence. The analysis of communities of networks of motifs is shown to be able to correlate sequences with functions in the human proteome database, to detect hot topics from online social dialogs, to characterize trajectories of dynamical systems, and it might find other useful applications to process large amounts of data in various fields.

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  • Received 4 February 2010

DOI:https://doi.org/10.1103/PhysRevLett.105.178702

© 2010 The American Physical Society

Authors & Affiliations

Roberta Sinatra1,2,*, Daniele Condorelli2,3, and Vito Latora1,2

  • 1Dipartimento di Fisica ed Astronomia, Università di Catania, and INFN, Via S. Sofia 64, 95123 Catania, Italy
  • 2Laboratorio sui Sistemi Complessi, Scuola Superiore di Catania, Via San Nullo 5/i, 95123 Catania, Italy
  • 3Dipartimento di Scienze Chimiche, Sezione di Biochimica e Biologia Molecolare, Università di Catania, Viale A. Doria 6, 95125 Catania, Italy

  • *Corresponding author. roberta.sinatra@ct.infn.it

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Issue

Vol. 105, Iss. 17 — 22 October 2010

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