Abstract
We discuss generalizations of a previously published coarse-grained description [Mergell et al., Phys. Rev. E 68, 021911 (2003)] of double stranded DNA (dsDNA). The model is defined at the base-pair level and includes the electrostatic repulsion between neighbor helices. We show that the model reproduces mechanical and elastic properties of several DNA nanostructures (DNA origamis). We also show that electrostatic interactions are necessary to reproduce atomic force microscopy measurements on planar DNA origamis.
9 More- Received 31 August 2012
DOI:https://doi.org/10.1103/PhysRevE.86.051912
©2012 American Physical Society
Synopsis
The Blueprint for DNA Origami
Published 21 November 2012
A new model of DNA is able to reproduce the observed features of self-organizing nanostructures in DNA origami.
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