Probabilistic cellular automaton describing a biological immune system

Tânia Tomé and J. R. Drugowich de Felício
Phys. Rev. E 53, 3976 – Published 1 April 1996
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Abstract

We have analyzed a probabilistic cellular automaton to describe the T-helper cells response under parasitic infections. The evolution rules are of totalistic type and possess "up-down" symmetry. The automaton displays a dynamical phase transition, from a disordered state to an ordered one, which takes place through a spontaneous symmetry breaking. In the ordered phase, one type of T-helper cells predominates over the others. The phase transition was studied both by a pair approximation and by Monte Carlo simulations. In addition, we were able to obtain some exact results for the densities of T-helper cells.

  • Received 21 August 1995

DOI:https://doi.org/10.1103/PhysRevE.53.3976

©1996 American Physical Society

Authors & Affiliations

Tânia Tomé

  • Instituto de Física, Universidade de São Paulo, Caixa Postal 66318 05389-970 São Paulo, São Paulo, Brazil

J. R. Drugowich de Felício

  • Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, 14040-901 Ribeirão Preto, São Paulo, Brazil and Instituto de Física de São Carlos, Universidade de São Paulo, 13560-000 São Carlos, São Paulo, Brazil

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Vol. 53, Iss. 4 — April 1996

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