Entropies of biosequences: The role of repeats

Hanspeter Herzel, Werner Ebeling, and Armin O. Schmitt
Phys. Rev. E 50, 5061 – Published 1 December 1994
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Abstract

DNA sequences of higher organisms contain thousands of nearly identical dispersed repetitive sequences. In order to understand the effect of such repeats on word entropies, we construct a model that can be analyzed analytically. The hypothetical model sequences consist of independent equidistributed symbols with randomly interspersed repeats. As a conclusion, we predict that the entropy of DNA sequences measuring the information content is much lower than suggested by earlier empirical studies.

  • Received 23 May 1994

DOI:https://doi.org/10.1103/PhysRevE.50.5061

©1994 American Physical Society

Authors & Affiliations

Hanspeter Herzel

  • Institute of Theoretical Physics, Technical University, Hardenbergstrasse 36, D-10623 Berlin, Germany

Werner Ebeling and Armin O. Schmitt

  • Institute of Physics, Humboldt University, Invalidenstrasse 110, D-10115 Berlin, Germany

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Vol. 50, Iss. 6 — December 1994

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