Simultaneous Imaging of Magnetic Nanoparticle Concentration, Temperature, and Viscosity

Jing Zhong, Meinhard Schilling, and Frank Ludwig
Phys. Rev. Applied 16, 054005 – Published 2 November 2021
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Abstract

In the coming era of precision medicine, there is a high demand for the development of approaches for in vivo tracking of biomolecules and measurements of their local environments. In this work, we present an approach for the simultaneous imaging of magnetic nanoparticle (MNP) concentration, temperature, and viscosity. The proposed approach allows one to determine the spatial distribution of the MNPs, while the MNPs are used as nanosensors for simultaneous measurements of the spatial distributions of temperature and viscosity. This technique has great potential for providing not only tools for disease diagnostics and therapy, but also insights into further understanding of the biophysical mechanisms involved in tumor tissues during cancer development and tumor metastasis.

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  • Received 8 January 2021
  • Revised 29 July 2021
  • Accepted 14 October 2021

DOI:https://doi.org/10.1103/PhysRevApplied.16.054005

© 2021 American Physical Society

Physics Subject Headings (PhySH)

Interdisciplinary PhysicsCondensed Matter, Materials & Applied PhysicsGeneral Physics

Authors & Affiliations

Jing Zhong1,2,*, Meinhard Schilling1, and Frank Ludwig1

  • 1Institut für Elektrische Messtechnik und Grundlagen der Elektrotechnik, TU Braunschweig, Braunschweig, Germany
  • 2School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China

  • *j.zhong@tu-braunschweig.de

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Issue

Vol. 16, Iss. 5 — November 2021

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