Dynamic Concentration of Motors in Microtubule Arrays

François Nédélec, Thomas Surrey, and A. C. Maggs
Phys. Rev. Lett. 86, 3192 – Published 2 April 2001
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Abstract

We present experimental and theoretical studies of the dynamics of molecular motors in microtubule arrays and asters. By solving a convection-diffusion equation we find that the density profile of motors in a two-dimensional aster is characterized by continuously varying exponents. Simulations are used to verify the assumptions of the continuum model. We observe the concentration profiles of kinesin moving in quasi-two-dimensional artificial asters by fluorescent microscopy and compare with our theoretical results.

  • Received 9 October 2000

DOI:https://doi.org/10.1103/PhysRevLett.86.3192

©2001 American Physical Society

Authors & Affiliations

François Nédélec1, Thomas Surrey1, and A. C. Maggs2

  • 1EMBL, Cell Biology, Meyerhofstrasse 1, 69115 Heidelberg, Germany
  • 2ESPCI, CNRS, PCT, 10 Rue Vauquelin, 75005 Paris, France

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Vol. 86, Iss. 14 — 2 April 2001

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