Hairpin Formation and Elongation of Biomolecules

Andrea Montanari and Marc Mézard
Phys. Rev. Lett. 86, 2178 – Published 5 March 2001
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Abstract

We introduce a model of thermalized conformations in space of RNA—or single stranded DNA—molecules, which includes the possibility of hairpin formation. This model contains the usual secondary structure information, but extends it to the study of one element of the ternary structure, namely the end-to-end distance. The computed force-elongation characteristics are in good agreement with some recent measurements on single stranded DNA molecules.

  • Received 12 June 2000

DOI:https://doi.org/10.1103/PhysRevLett.86.2178

©2001 American Physical Society

Authors & Affiliations

Andrea Montanari1 and Marc Mézard2

  • 1Scuola Normale Superiore and INFN–Sezione di Pisa, I-56100 Pisa, Italy
  • 2Laboratoire de Physique Théorique et Modèles Statistiques, Université Paris Sud, Batiment 100, 91 405 Orsay Cedex, France

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Issue

Vol. 86, Iss. 10 — 5 March 2001

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