Long-range anticorrelations and non-Gaussian behavior of the heartbeat

C.-K. Peng, J. Mietus, J. M. Hausdorff, S. Havlin, H. E. Stanley, and A. L. Goldberger
Phys. Rev. Lett. 70, 1343 – Published 1 March 1993
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Abstract

We find that the successive increments in the cardiac beat-to-beat interals of healthy subjects display scale-invariant, long-range anticorrelations (up to 104 heart beats). Furthermore, we find that the histogram for the heartbeat intervals increments is well described by a Lévy stable distribution. For a group of subjects with severe heart disease, we find that the distribution is unchanged, but the long-range correlations vanish. Therefore, the different scaling behavior in health and disease must relate to the underlying dynamics of the heartbeat.

  • Received 15 October 1992

DOI:https://doi.org/10.1103/PhysRevLett.70.1343

©1993 American Physical Society

Authors & Affiliations

C.-K. Peng, J. Mietus, J. M. Hausdorff, S. Havlin, H. E. Stanley, and A. L. Goldberger

  • Center for Polymer Studies and Department of Physics, Boston University, Boston, Massachusetts 02215
  • Cardiovascular Division, Harvard Medical School, Beth Israel Hospital, Boston, Massachusetts 02215
  • Physical Sciences Laboratory, Division of Computer Research and Technology, National Institutes of Health, Bethesda, Maryland 20892

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Vol. 70, Iss. 9 — 1 March 1993

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