Abstract
We explore emergent effects of multidimensionality of the free energy landscape on single-molecule kinetics under constant force. The proposed minimal model reveals the existence of a spectrum of unusual scenarios for the force-dependent lifetime, all of which are shown to occur on a free energy landscape with a single transition state. We present an analytical solution that governs single-molecule responses to a constant force and relates them to microscopic parameters of the system.
- Received 27 August 2009
DOI:https://doi.org/10.1103/PhysRevLett.104.048101
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