Comment on “Correlated noise in a logistic growth model”

Anita Behera and S. Francesca C. O’Rourke
Phys. Rev. E 77, 013901 – Published 22 January 2008

Abstract

We argue that the results published by Ai et al. [Phys. Rev. E 67, 022903 (2003)] on “correlated noise in logistic growth” are not correct. Their conclusion that, for larger values of the correlation parameter λ, the cell population is peaked at x=0, which denotes a high extinction rate, is also incorrect. We find the reverse behavior to their results, that increasing λ promotes the stable growth of tumor cells. In particular, their results for the steady-state probability, as a function of cell number, at different correlation strengths, presented in Figs. 1 and 2 of their paper show different behavior than one would expect from the simple mathematical expression for the steady-state probability. Additionally, their interpretation that at small values of cell number the steady-state probability increases as the correlation parameter is increased is also questionable. Another striking feature in their Figs. 1 and 3 is that, for the same values of the parameters λ and α, their simulation produces two different curves, both qualitatively and quantitatively.

  • Figure
  • Figure
  • Received 4 May 2007

DOI:https://doi.org/10.1103/PhysRevE.77.013901

©2008 American Physical Society

Authors & Affiliations

Anita Behera and S. Francesca C. O’Rourke*

  • School of Biomedical Sciences, The Queen’s University of Belfast, Belfast BT9 7AB, United Kingdom

  • *Also at Department of Applied Mathematics and Theoretical Physics. s.orourke@qub.ac.uk

Comments & Replies

Reply to “Comment on ‘Correlated noise in a logistic growth model’ ”

Bao-quan Ai, Xian-ju Wang, and Liang-gang Liu
Phys. Rev. E 77, 013902 (2008)

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Original Article

Correlated noise in a logistic growth model

Bao-Quan Ai, Xian-Ju Wang, Guo-Tao Liu, and Liang-Gang Liu
Phys. Rev. E 67, 022903 (2003)

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Vol. 77, Iss. 1 — January 2008

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