Temperature dependence of formation of a supported phospholipid bilayer from vesicles on ${\mathrm{SiO}}_2$

Adsorption of egg-phosphatidylcholine vesicles and bilayer formation on a ${\mathrm{SiO}}_2$ surface was investigated in the temperature range 278–303 K using the quartz crystal microbalance-dissipation technique. The critical coverage for the $\mathrm{vesicle}\to \mathrm{bilayer}$ transition is found to decrease with increasing temperature. The temperature dependence of the time-scale characterizing this transition can be represented in the Arrhenius form. Higher temperatures produce a bilayer with fewer trapped, nonruptured vesicles.