Conformations of linear DNA

Boris Fain, Joseph Rudnick, and Stellan Östlund
Phys. Rev. E 55, 7364 – Published 1 June 1997
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Abstract

We examine the conformations of a model for underwound and overwound DNA. The molecule is represented as a cylindrically symmetric elastic string subjected to a stretching force and to constraints corresponding to a specification of the link number. We derive a fundamental relation between the Euler angles that describe the curve and the topological linking number. Analytical expressions for the spatial configurations of the molecule in the infinite-length limit are obtained. A unique configuration minimizes the energy for a given set of physical conditions. An elastic model incorporating thermal fluctuations provides excellent agreement with experimental results on the plectonemic transition.

    DOI:https://doi.org/10.1103/PhysRevE.55.7364

    ©1997 American Physical Society

    Authors & Affiliations

    Boris Fain and Joseph Rudnick

    • Department of Physics, University of California, Los Angeles, California 90095

    Stellan Östlund

    • Institute for Theoretical Physics, Chalmers Institute of Technology, Gothenberg, Sweden

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    Issue

    Vol. 55, Iss. 6 — June 1997

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