Abstract
The Stokes-Einstein equation is applied to the water self-diffusion coefficient D in human serum albumin protein solutions. A linear trend for D as a function of T/η is found for all the protein concentrations investigated. However, the indication of a violation of the Stokes-Einstein equation is found in the protein concentration dependence of the effective hydrodynamic radius of water. The deviation of the experimental NMR water self-diffusion and viscosity data from the hydrodynamic Stokes-Einstein relation is found to be consistent with an enhancement of the solvent structure in the vicinity of the protein surface.
- Received 22 February 1994
DOI:https://doi.org/10.1103/PhysRevE.49.5878
©1994 American Physical Society