Abstract
Long-range power-law correlations have been reported recently for DNA sequences containing noncoding regions. We address the question of whether such correlations may be a trivial consequence of the known mosaic structure (‘‘patchiness’’) of DNA. We analyze two classes of controls consisting of patchy nucleotide sequences generated by different algorithms—one without and one with long-range power-law correlations. Although both types of sequences are highly heterogeneous, they are quantitatively distinguishable by new fluctuation analysis method that differentiates local patchiness from long-range correlations. Application of this analysis to selected DNA sequences demonstrates that patchiness is not sufficient to account for long-range correlation properties.
- Received 20 October 1993
DOI:https://doi.org/10.1103/PhysRevE.49.1685
©1994 American Physical Society
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Physical Review E 25th Anniversary Milestones
The year 2018 marks the 25th anniversary of Physical Review E. To celebrate the journal’s rich legacy, during the upcoming year we highlight a series of papers that made important contributions to their field. These milestone articles were nominated by members of the Editorial Board of Physical Review E, in collaboration with the journal’s editors. The 25 milestone articles, including an article for each calendar year from 1993 through 2017 and spanning all major subject areas of the journal, will be unveiled in chronological order and will be featured on the journal website.