DNA denaturation as a problem of translational-symmetry restoration

Carla Goldman and Wilma K. Olson
Phys. Rev. E 48, 1461 – Published 1 August 1993
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Abstract

We study the quantum-mechanical version of a model proposed by Peyrard and Bishop [Phys. Rev. Lett. 62, 2755 (1989)] to describe the denaturation phenomenon on the DNA double helix. We characterize denaturation as a phase transition leading to the restoration of the translational invariance of the system. The problem is approached via a modified perturbative theory which incorporates also nonperturbative effects. These are accounted by an auxiliary random variable u describing the equilibrium positions of the constituting particles. The criticality of the model is revealed by analyzing equations involving the first and second cumulants of the u-distribution function. As a consequence, an analytical expression for the critical temperature Tc is obtained as a function of all model parameters.

  • Received 12 March 1993

DOI:https://doi.org/10.1103/PhysRevE.48.1461

©1993 American Physical Society

Authors & Affiliations

Carla Goldman and Wilma K. Olson

  • Department of Chemistry, Wright-Rieman Laboratory, Rutgers University, P.O. Box 939, Piscataway, New Jersey 08855

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Issue

Vol. 48, Iss. 2 — August 1993

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